Ω OmegAMP

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Measured at each peptide's MIC against A. baumannii ATCC 19606
NPN — Outer membrane permeabilization
DiSC3(5) — Membrane depolarization
NPN vs DiSC MaxRel — Mechanistic profile
Fixed concentration (per-family, see tooltip for conc.)
NPN — Outer membrane permeabilization
DiSC3(5) — Membrane depolarization
NPN vs DiSC MaxRel — Mechanistic profile
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LPS neutralization — BC probe displacement (%)
2 μM
8 μM
32 μM
32 μM + Ca²⁺
DNA binding — ΔA
12.5 μM
25 μM
50 μM
ΔAmax
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Murine Model
Skin scarification — A. baumannii ATCC 19606
Bacterial burden at endpoint
Body-weight change
Proteolytic stability
% remaining peptide over time (protease exposure) — the systemic-model filter
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Thigh infection — A. baumannii ATCC 19606 (neutropenic)
Bacterial burden at endpoint
Body-weight change
Compare Selected Peptides
Click any peptide in the other tabs to select it. Click again to deselect. Select up to 10 peptides to compare them here.